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High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy

Most of the human tumor-associated antigens (TAAs) characterized thus far are derived from nonmutated “self”-proteins. Numerous strategies have been developed to break tolerance to TAAs, combining various forms of antigens with different vectors and adjuvants. However, no study has yet determined ho...

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Detalhes bibliográficos
Main Authors: Gross, David-Alexandre, Graff-Dubois, Stéphanie, Opolon, Paule, Cornet, Sébastien, Alves, Pedro, Bennaceur-Griscelli, Annelise, Faure, Olivier, Guillaume, Philippe, Firat, Hüseyin, Chouaib, Salem, Lemonnier, François A., Davoust, Jean, Miconnet, Isabelle, Vonderheide, Robert H., Kosmatopoulos, Kostas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC324537/
https://ncbi.nlm.nih.gov/pubmed/14755339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419418
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