Epstein-Barr Virus Evades CD4(+) T Cell Responses in Lytic Cycle through BZLF1-mediated Downregulation of CD74 and the Cooperation of vBcl-2

Evasion of immune T cell responses is crucial for viruses to establish persistence in the infected host. Immune evasion mechanisms of Epstein-Barr virus (EBV) in the context of MHC-I antigen presentation have been well studied. In contrast, viral interference with MHC-II antigen presentation is less...

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Detalhes bibliográficos
Main Authors: Zuo, Jianmin, Thomas, Wendy A., Haigh, Tracey A., Fitzsimmons, Leah, Long, Heather M., Hislop, Andrew D., Taylor, Graham S., Rowe, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245307/
https://ncbi.nlm.nih.gov/pubmed/22216005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002455
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