Intranasal Immunization of the Combined Lipooligosaccharide Conjugates Protects Mice from the Challenges with Three Serotypes of Moraxella catarrhalis

BACKGROUND: There are no licensed vaccines available against Moraxella catarrhalis, a significant human respiratory pathogen. Lipooligosaccharide (LOS) based conjugate vaccines derived from individual serotype M. catarrhalis only showed partial protection coverage. A vaccine combining LOS conjugates...

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Detalhes bibliográficos
Main Authors: Ren, Dabin, Xie, Hang, Zhang, Wenhong, Hassan, Ferdaus, Petralia, Ronald S., Yu, Shengqing, Lim, David J., Gu, Xin-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245267/
https://ncbi.nlm.nih.gov/pubmed/22216312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029553
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