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Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling

The Aspergillus pal pathway hijacks ESCRT proteins into ambient pH signalling complexes. We show that components of ESCRT-0, ESCRT-I, ESCRT-II and ESCRT-III are nearly essential for growth, precluding assessment of null mutants for pH signalling or trafficking. This severely debilitating effect is r...

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Main Authors: Calcagno-Pizarelli, Ana M., Hervás-Aguilar, América, Galindo, Antonio, Abenza, Juan F., Peñalva, Miguel A., Arst, Herbert N.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244986/
https://ncbi.nlm.nih.gov/pubmed/22135362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.088344
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