Early Th1 Cell Differentiation Is Marked by A Tfh-like Cell Transition

Follicular helper T (Tfh) cells comprise an important subset of helper T cells; however, their relationship with other helper lineages is incompletely understood. Herein, we showed interleukin-12 acting via the transcription factor STAT4 induced both Il21 and Bcl6 genes, generating cells with featur...

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Detalhes bibliográficos
Main Authors: Nakayamada, Shingo, Kanno, Yuka, Takahashi, Hayato, Jankovic, Dragana, Lu, Kristina T., Johnson, Thomas A., Sun, Hong-wei, Vahedi, Golnaz, Hakim, Ofir, Handon, Robin, Schwartzberg, Pamela L., Hager, Gordon L., O’Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244883/
https://ncbi.nlm.nih.gov/pubmed/22195747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.11.012
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