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STAT3: A Target to Enhance Antitumor Immune Response
Signal transducer and activator of transcription 3 (Stat3) has emerged as a critical regulator for tumor-associated inflammation. Activation of Stat3 negatively regulates the Th1-type immune response and promotes expansion of myeloid-derived suppressor cells (MDSCs) and regulatory T-cell functions i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244828/ https://ncbi.nlm.nih.gov/pubmed/20517723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2010_51 |
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