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Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers

Motivation: Genome-wide mRNA profiling provides a snapshot of the global state of cells under different conditions. However, mRNA levels do not provide direct understanding of upstream regulatory mechanisms. Here, we present a new approach called Expression2Kinases (X2K) to identify upstream regulat...

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Detalhes bibliográficos
Main Authors: Chen, Edward Y., Xu, Huilei, Gordonov, Simon, Lim, Maribel P., Perkins, Matthew H., Ma'ayan, Avi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244772/
https://ncbi.nlm.nih.gov/pubmed/22080467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr625
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