Dosing equation for tacrolimus using genetic variants and clinical factors

AIM: To develop a dosing equation for tacrolimus, using genetic and clinical factors from a large cohort of kidney transplant recipients. Clinical factors and six genetic variants were screened for importance towards tacrolimus clearance (CL/F). METHODS: Clinical data, tacrolimus troughs and corresp...

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Detalhes bibliográficos
Main Authors: Passey, Chaitali, Birnbaum, Angela K, Brundage, Richard C, Oetting, William S, Israni, Ajay K, Jacobson, Pamala A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244642/
https://ncbi.nlm.nih.gov/pubmed/21671989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04039.x
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