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Growth, metastasis, and expression of CCL2 and CCL5 by murine mammary carcinomas are dependent upon Myd88

Previously we reported that lipopolysaccharide (LPS) treatment of murine mammary carcinomas resulted in decreased growth of the tumors. Here we show the decreased growth following LPS treatment was mediated through effects downstream of TLR4 and Myd88. Perhaps more notably, simply reducing TLR4 or M...

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Detalhes bibliográficos
Main Authors: Egunsola, Adetutu T., Zawislak, Carolyn L., Akuffo, Afua A., Chalmers, Samantha A., Ewer, Jason C., Vail, Caroline M., Lombardo, Jeffrey C., Perez, Dana N., Kurt, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244535/
https://ncbi.nlm.nih.gov/pubmed/22088941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.10.008
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