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Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing()

Secondary antibody variable region gene segment rearrangement, termed receptor editing, is a major mechanism contributing to B lymphocyte self tolerance. However, the parameters that determine whether a B cell undergoes editing or not are a current subject of debate. We tested the role that level of...

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Hlavní autoři: Shen, Shixue, Manser, Tim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244530/
https://ncbi.nlm.nih.gov/pubmed/22131331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102109
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