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Multi-Scale Stochastic Simulation of Diffusion-Coupled Agents and Its Application to Cell Culture Simulation

Many biological systems consist of multiple cells that interact by secretion and binding of diffusing molecules, thus coordinating responses across cells. Techniques for simulating systems coupling extracellular and intracellular processes are very limited. Here we present an efficient method to sto...

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Detalhes bibliográficos
Main Authors: Shimoni, Yishai, Nudelman, German, Hayot, Fernand, Sealfon, Stuart C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244460/
https://ncbi.nlm.nih.gov/pubmed/22216238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029298
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