Heterologous Expression of Membrane Proteins: Choosing the Appropriate Host

BACKGROUND: Membrane proteins are the targets of 50% of drugs, although they only represent 1% of total cellular proteins. The first major bottleneck on the route to their functional and structural characterisation is their overexpression; and simply choosing the right system can involve many months...

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Detalhes bibliográficos
Main Authors: Bernaudat, Florent, Frelet-Barrand, Annie, Pochon, Nathalie, Dementin, Sébastien, Hivin, Patrick, Boutigny, Sylvain, Rioux, Jean-Baptiste, Salvi, Daniel, Seigneurin-Berny, Daphné, Richaud, Pierre, Joyard, Jacques, Pignol, David, Sabaty, Monique, Desnos, Thierry, Pebay-Peyroula, Eva, Darrouzet, Elisabeth, Vernet, Thierry, Rolland, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244453/
https://ncbi.nlm.nih.gov/pubmed/22216205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029191
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