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Luminescent-Activated Transfected Killer Cells to Monitor Leukocyte Trafficking During Systemic Bacterial and Fungal Infection

Background. Activated transfected killer (ATAK) cells are immortal phagocytes transfected with a luminescence reporter that effectively treat lethal infections in neutropenic mice. Their in vivo trafficking, lifespan, and immunogenicity are unknown. Methods. Mice were made neutropenic; infected or n...

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Main Authors: Lin, Lin, Ibrahim, Ashraf S., Baquir, Beverlie, Palosaari, Andrew, Spellberg, Brad
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244365/
https://ncbi.nlm.nih.gov/pubmed/22124127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir725
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