Evolutionary Ecology of Human Papillomavirus: Trade-offs, Coexistence, and Origins of High-Risk and Low-Risk Types

Background. We address the ecological and evolutionary dynamics of human papillomavirus (HPV) that lead to the dichotomy between high-risk (HR) and low-risk (LR) types. We hypothesize that HPV faces an evolutionary tradeoff between persistence and per-contact transmission probability. High virion pr...

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Библиографические подробности
Главные авторы: Orlando, Paul A., Gatenby, Robert A., Giuliano, Anna R., Brown, Joel S.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244363/
https://ncbi.nlm.nih.gov/pubmed/22090448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir717
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