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Akt inhibitors in clinical development for the treatment of cancer
IMPORTANCE OF THE FIELD: The evolution of targeted therapies is dependent upon identification of cellular moieties that can be pharmacologically modulated. As one such example, the serine-threonine kinase Akt was identified nearly two decades ago. Since then, its role in mediating multiple signaling...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244346/ https://ncbi.nlm.nih.gov/pubmed/20846000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2010.520701 |
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