The Cell Fate Determination Factor DACH1 Is Expressed in Estrogen Receptor-α–Positive Breast Cancer and Represses Estrogen Receptor-α Signaling

The Dachshund (dac) gene, initially cloned as a dominant inhibitor of the Drosophila hyperactive EGFR mutant ellipse, encodes a key component of the cell fate determination pathway involved in Drosophila eye development. Analysis of more than 2,200 breast cancer samples showed improved survival by s...

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Main Authors: Popov, Vladimir M., Zhou, Jie, Shirley, L. Andrew, Quong, Judy, Yeow, Wen-Shuz, Wright, Jennifer A., Wu, Kongming, Rui, Hallgeir, Vadlamudi, Ratna K., Jiang, Jie, Kumar, Rakesh, Wang, Chenguang, Pestell, Richard G.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244171/
https://ncbi.nlm.nih.gov/pubmed/19605405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3992
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