Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity

Toll-like receptor 4 (TLR4), which signals through the adapter molecules myeloid differentiation factor 88 (MyD88) and toll/interleukin 1 receptor domain-containing adapter inducing IFN-β (TRIF), is required for protection against Gram-negative bacteria. TRIF is known to be important in TLR3-mediate...

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Detalhes bibliográficos
Main Authors: Sotolongo, John, España, Cecilia, Echeverry, Andrea, Siefker, David, Altman, Norman, Zaias, Julia, Santaolalla, Rebeca, Ruiz, Jose, Schesser, Kurt, Adkins, Becky, Fukata, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244044/
https://ncbi.nlm.nih.gov/pubmed/22124111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110547
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