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Use of a Drosophila Genome-Wide Conserved Sequence Database to Identify Functionally Related cis-Regulatory Enhancers

Background: Phylogenetic footprinting has revealed that cis-regulatory enhancers consist of conserved DNA sequence clusters (CSCs). Currently, there is no systematic approach for enhancer discovery and analysis that takes full-advantage of the sequence information within enhancer CSCs. Results: We h...

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Detalhes bibliográficos
Main Authors: Brody, Thomas, Yavatkar, Amarendra S, Kuzin, Alexander, Kundu, Mukta, Tyson, Leonard J, Ross, Jermaine, Lin, Tzu-Yang, Lee, Chi-Hon, Awasaki, Takeshi, Lee, Tzumin, Odenwald, Ward F
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Liss, Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243966/
https://ncbi.nlm.nih.gov/pubmed/22174086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22728
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