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Significance of ER–Src axis in hormonal therapy resistance

The estrogen receptor (ER) is implicated in the progression of breast cancer. Despite positive effects of hormonal therapy, initial or acquired resistance to endocrine therapies frequently occurs. Recent studies suggested ERα-coregulator PELP1 and growth factor receptor ErbB2/HER2 play an essential...

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Hlavní autoři: Vallabhaneni, Sreeram, Nair, Binoj C., Cortez, Valerie, Challa, Rambabu, Chakravarty, Dimple, Tekmal, Rajeshwar Rao, Vadlamudi, Ratna K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243930/
https://ncbi.nlm.nih.gov/pubmed/21184269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1312-2
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