Predicting IGF-1R therapy response in bone sarcomas: immuno-SPECT imaging with radiolabeled R1507

PURPOSE: To investigate whether (111)In-R1507 immuno-SPECT, a novel non-invasive, in vivo screening method to visualize membranous Insulin-like Growth Factor 1 Receptor (IGF-1R) expression and accessibility, can be used to predict IGF-1R treatment (R1507) responsein bone sarcomas. EXPERIMENTAL DESIG...

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Auteurs principaux: Fleuren, Emmy D.G., Versleijen-Jonkers, Yvonne M.H., van de Luijtgaarden, Addy C.M., Molkenboer-Kuenen, Janneke D.M., Heskamp, Sandra, Roeffen, Melissa H.S., van Laarhoven, Hanneke W.M., Houghton, Peter J., Oyen, Wim J.G., Boerman, Otto C., van der Graaf, Winette T.A.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243810/
https://ncbi.nlm.nih.gov/pubmed/22038993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1488
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