Comparative Metabolomic and Genomic Analyses of TCDD-Elicited Metabolic Disruption in Mouse and Rat Liver

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicits a broad spectrum of species-specific effects that have not yet been fully characterized. This study compares the temporal effects of TCDD on hepatic aqueous and lipid metabolite extracts from immature ovariectomized C57BL/6 mice and Sprague-Dawley r...

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Autores principales: Forgacs, Agnes L., Kent, Michael N., Makley, Meghan K., Mets, Bryan, DelRaso, Nicholas, Jahns, Gary L., Burgoon, Lyle D., Zacharewski, Timothy R., Reo, Nicholas V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Environmental Toxicology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243745/
https://ncbi.nlm.nih.gov/pubmed/21964420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr262
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