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miR451 and AMPK Mutual Antagonism in Glioma Cell Migration and Proliferation: A Mathematical Model

Glioblastoma multiforme (GBM) is the most common and the most aggressive type of brain cancer; the median survival time from the time of diagnosis is approximately one year. GBM is characterized by the hallmarks of rapid proliferation and aggressive invasion. miR-451 is known to play a key role in g...

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Autori principali: Kim, Yangjin, Roh, Soyeon, Lawler, Sean, Friedman, Avner
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243681/
https://ncbi.nlm.nih.gov/pubmed/22205943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028293
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