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The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline

In a broad range of organisms, Piwi-interacting RNAs (piRNAs) have emerged as core components of a surveillance system that protects the genome by silencing transposable and repetitive elements. A vast proportion of piRNAs is produced from discrete genomic loci, termed piRNA clusters, which are gene...

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Autori principali: Pane, Attilio, Jiang, Peng, Zhao, Dorothy Yanling, Singh, Mona, Schüpbach, Trudi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243597/
https://ncbi.nlm.nih.gov/pubmed/21952049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.334
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