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Origins of Specificity and Promiscuity in Metabolic Networks
How enzymes have evolved to their present form is linked to the question of how pathways emerged and evolved into extant metabolic networks. To investigate this mechanism, we have explored the chemical diversity present in a largely unbiased data set of catalytic reactions processed by modern enzyme...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243566/ https://ncbi.nlm.nih.gov/pubmed/22052908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274050 |
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