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Localization of SV40 genes within supercoiled loop domains.

Recent studies indicate that eukaryotic DNA is organized into supercoiled loop domains. These loops appear to be anchored at their bases to an insoluble nuclear skeleton or matrix. Most of the DNA in the loops can be released from the matrix by nuclease digestion; the residual DNA remaining with the...

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Bibliographic Details
Main Authors: Nelkin, B D, Pardoll, D M, Vogelstein, B
Format: Artigo
Language:Inglês
Published: 1980
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC324330/
https://ncbi.nlm.nih.gov/pubmed/6258148
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