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Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.

Synthesis of two oligothymidylic acids, tridecamer and nonadecamer, is described by a rapid and simple solid-phase method on two kinds of polyacrylamide supports derivatized from commercially available Enzacryl Gel K-2. The syntheses were performed by the phosphotriester method using di- and tri-thy...

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Autores principales: Miyoshi, K, Miyake, T, Hozumi, T, Itakura, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1980
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC324315/
https://ncbi.nlm.nih.gov/pubmed/7465418
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