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MULTIPLE WAYS TO DIE: DELINEATION OF THE UNFOLDED PROTEIN RESPONSE AND APOPTOSIS INDUCED BY SURFACTANT PROTEIN C BRICHOS MUTANTS

Epithelial cell dysfunction is now recognized as an important mechanism in the pathogenesis of interstitial lung diseases. Surfactant Protein C (SP-C), an alveolar type II cell specific protein, has contributed to this concept with the observation that heterozygous expression of SFTPC gene mutations...

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Autors principals: Maguire, Jean Ann, Mulugeta, Surafel, Beers, Michael F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243113/
https://ncbi.nlm.nih.gov/pubmed/22016030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2011.10.003
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