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The Cyc8–Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein
The yeast Tup1–Cyc8 corepressor complex is recruited to promoters by DNA-binding repressors, but the mechanisms by which it inhibits expression of genes involved in various stress pathways are poorly understood. Conditional and rapid depletion of Tup1 from the nucleus leads to concurrent nucleosome...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243062/ https://ncbi.nlm.nih.gov/pubmed/22156212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179275.111 |
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