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CD4(+) T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants

RATIONALE: While microvascular injury is associated with chronic rejection, the cause of tissue ischemia during alloimmune injury is not yet elucidated. OBJECTIVE: We investigated the contribution of T lymphocytes and complement to microvascular injury-associated ischemia during acute rejection of m...

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Detalhes bibliográficos
Main Authors: Khan, Mohammad A., Jiang, Xinguo, Dhillon, Gundeep, Beilke, Joshua, Holers, V. Michael, Atkinson, Carl, Tomlinson, Stephen, Nicolls, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243047/
https://ncbi.nlm.nih.gov/pubmed/21998328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.250167
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