Deficiency of Foxp3(+) Regulatory T Cells Exacerbates Autoimmune Arthritis by Altering the Synovial Proportions of CD4(+) T Cells and Dendritic Cells

BACKGROUND: CD4(+)Fop3(+) regulatory T cells (Tregs) are needed to maintain peripheral tolerance, but their role in the development of autoimmune arthritis is still debated. The present study was undertaken to investigate the mechanism by which Tregs influence autoimmune arthritis, using a mouse mod...

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Hlavní autoři: Jang, Eunkyeong, Cho, Mi La, Oh, Hye-Joa, Youn, Jeehee
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Association of Immunologists 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243004/
https://ncbi.nlm.nih.gov/pubmed/22194713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2011.11.5.299
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