Smooth Muscle Myosin Light Chain Kinase Efficiently Phosphorylates Serine 15 of Cardiac Myosin Regulatory Light Chain

Specific phosphorylation of the human ventricular cardiac myosin regulatory light chain (MYL2) modifies the protein at S15. This modification affects MYL2 secondary structure and modulates the Ca(2+) sensitivity of contraction in cardiac tissue. Smooth muscle myosin light chain kinase (smMLCK) is a...

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Autores principales: Josephson, Matthew P., Sikkink, Laura A., Penheiter, Alan R., Burghardt, Thomas P., Ajtai, Katalin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242870/
https://ncbi.nlm.nih.gov/pubmed/22120626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.044
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