Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate

Autophagy is a cellular response to starvation which generates autophagosomes to carry cellular organelles and long-lived proteins to lysosomes for degradation. Degradation through autophagy can provide an innate defense against virus infection, or conversely autophagosomes can promote infection by...

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Hlavní autoři: Cottam, Eleanor M, Maier, Helena J, Manifava, Maria, Vaux, Laura C, Chandra-Schoenfelder, Priya, Gerner, Wilhelm, Britton, Paul, Ktistakis, Nick T, Wileman, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242798/
https://ncbi.nlm.nih.gov/pubmed/21799305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.11.16642
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