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Suppression and Regression of Choroidal Neovascularization in Mice by a Novel CCR2 Antagonist, INCB3344

PURPOSE: To investigate the effect of an intravitreally administered CCR2 antagonist, INCB3344, on a mouse model of choroidal neovascularization (CNV). METHODS: CNV was induced by laser photocoagulation on Day 0 in wild type mice. INCB3344 or vehicle was administered intravitreally immediately after...

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Détails bibliographiques
Auteurs principaux: Xie, Ping, Kamei, Motohiro, Suzuki, Mihoko, Matsumura, Nagakazu, Nishida, Kentaro, Sakimoto, Susumu, Sakaguchi, Hirokazu, Nishida, Kohji
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242774/
https://ncbi.nlm.nih.gov/pubmed/22205983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028933
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