Effects of GF-015535-00, a Novel α1 GABA(A) Receptor Ligand, on the Sleep-Wake Cycle in Mice, with Reference to Zolpidem

STUDY OBJECTIVES: Novel, safe, and efficient hypnotic compounds capable of enhancing physiological sleep are still in great demand in the therapy of insomnia. This study compares the sleep-wake effects of a new α1 GABA(A) receptor subunit ligand, GF-015535-00, with those of zolpidem, the widely util...

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Bibliographic Details
Main Authors: Anaclet, Christelle, Zhang, Mei, Zhao, Chunmei, Buda, Colette, Seugnet, Laurent, Lin, Jian-Sheng
Format: Artigo
Language:Inglês
Published: Associated Professional Sleep Societies, LLC 2012
Subjects:
Effects of GF-015535-00 on the Sleep-Wake Cycle in Mice
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242675/
https://ncbi.nlm.nih.gov/pubmed/22215924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.1596
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