High rate of extra-haematological toxicity compromises dose-dense sequential adjuvant chemotherapy for breast cancer

BACKGROUND: A dose-dense strategy has been considered to improve results of adjuvant chemotherapy for breast cancer. This randomised phase II trial investigated the feasibility of this approach with sequential anthracyclines and taxanes-based chemotherapy. METHODS: Patients with high-risk node-posit...

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Detalhes bibliográficos
Main Authors: Brain, E, Levy, C, Serin, D, Roché, H, Spielmann, M, Delva, R, Veyret, C, Mauriac, L, Rios, M, Martin, A L, Jimenez, M, Asselain, B, Gauthier, M, Bonnetain, F, Fumoleau, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242527/
https://ncbi.nlm.nih.gov/pubmed/22009030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.414
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