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Termination of vitro DNA synthesis at AAF adducts in the DNA.

DNA synthesis catalyzed by E. coli polymerases I or III is inhibited on templates containing N-acetoxy-acetylaminofluorene-reacted adducts. Termination of synthesis occurs just before the site of the adduct. Synthesis on 0X174 templates primed with restriction fragments and treated with AAAF can be...

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Detalhes bibliográficos
Main Authors: Moore, P D, Rabkin, S D, Strauss, B S
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC324252/
https://ncbi.nlm.nih.gov/pubmed/6448988
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