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Termination of vitro DNA synthesis at AAF adducts in the DNA.
DNA synthesis catalyzed by E. coli polymerases I or III is inhibited on templates containing N-acetoxy-acetylaminofluorene-reacted adducts. Termination of synthesis occurs just before the site of the adduct. Synthesis on 0X174 templates primed with restriction fragments and treated with AAAF can be...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1980
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324252/ https://ncbi.nlm.nih.gov/pubmed/6448988 |
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