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Interactions between insulin-like growth factor-I, estrogen receptor-α (ERα) and ERβ in regulating growth/apoptosis of MCF-7 human breast cancer cells

Understanding of the interactions between estradiol (E2) and insulin-like growth factor-I (IGF-I) is still incomplete. Cell lines derived from the MCF-7 breast cancer cells were generated with suppressed expression of the IGF-I receptor (IGF-IR), termed IGF-IR.low cells, by stable transfection using...

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Detalhes bibliográficos
Main Authors: Mendoza, Rhone A., Enriquez, Marlene I, Mejia, Sylvia M, Moody, Emily E, Thordarson, Gudmundur
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242433/
https://ncbi.nlm.nih.gov/pubmed/20974640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0235
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