A carregar...

Persistent Cox-2 inhibition downregulates NF-κB resulting in chronic intestinal inflammation in the Min/+ mouse model of colon tumorigenesis

COX-2 inhibition prevents adenoma formation in humans and mouse models of colon cancer. The selective COX-2 inhibitor, celecoxib, reduces COX-2 and PGE(2) expression and adenomas in the intestine of Min/+ mice after treatment for several weeks, but prolonged treatment increases PGE(2) production, re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Carothers, Adelaide M., Davids, Jennifer S., Damas, Beatrice C., Bertagnolli, Monica M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242378/
https://ncbi.nlm.nih.gov/pubmed/20484034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4289
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!