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Corticotropin-Releasing Factor in the Norepinephrine Nucleus, Locus Coeruleus, Facilitates Behavioral Flexibility

Corticotropin-releasing factor (CRF), the stress-related neuropeptide, acts as a neurotransmitter in the brain norepinephrine nucleus, locus coeruleus (LC), to activate this system during stress. CRF shifts the mode of LC discharge from a phasic to a high tonic state that is thought to promote behav...

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Detalhes bibliográficos
Main Authors: Snyder, Kevin, Wang, Wei-Wen, Han, Rebecca, McFadden, Kile, Valentino, Rita J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242313/
https://ncbi.nlm.nih.gov/pubmed/21993205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.218
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