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Protective effects and mechanisms of sirtuins in the nervous system

Silent information regulator two proteins (sirtuins or SIRTs) are a group of histone deacetylases whose activities are dependent on and regulated by nicotinamide adenine dinucleotide (NAD(+)). They suppress genome-wide transcription, yet upregulate a select set of proteins related to energy metaboli...

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Hlavní autoři: Zhang, Feng, Wang, Suping, Gan, Li, Vosler, Peter S., Gao, Yanqin, Chen, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242010/
https://ncbi.nlm.nih.gov/pubmed/21930182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2011.09.001
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