TRANSGENIC OVEREXPRESSION OF NEUROGLOBIN ATTENUATES FORMATION OF SMOKE INHALATION-INDUCED OXIDATIVE DNA DAMAGE, IN VIVO, IN THE MOUSE BRAIN

Acute inhalation of combustion smoke causes neurological deficits in survivors. Inhaled smoke includes carbon monoxide, noxious gases and hypoxic environment, which disrupt oxygenation and generate free radicals. To replicate a smoke inhalation scenario, we developed experimental model of acute expo...

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Autores principales: Lee, Heung Man, Greeley, George H., Englander, Ella W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241998/
https://ncbi.nlm.nih.gov/pubmed/22001746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.09.026
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