Induction of Strong HIV-1-specific CD4(+) T Cell Responses using an HIV-1 gp120/NefTat Vaccine adjuvanted with AS02(A) in ARV Treated HIV-1-Infected Individuals

BACKGROUND: Induction of HIV-1-specific CD4+ T cell responses by therapeutic vaccination represents an attractive intervention to potentially increase immune control of HIV-1. METHODS: We performed a double-blinded, randomized, placebo-controlled clinical trial to determine the safety and immunogeni...

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Autors principals: Lichterfeld, Mathias, Gandhi, Rajesh T., Simmons, Rachel P., Flynn, Teresa, Sbrolla, Amy, Yu, Xu G., Basgoz, Nesli, Mui, Stanley, Williams, Katie, Streeck, Hendrik, Burgett-Yandow, Nicole, Roy, Gilbert, Janssens, Michel, Pedneault, Louise, Vandepapelière, Pierre, Koutsoukos, Marguerite, Demoitié, Marie-Ange, Bourguignon, Patricia, McNally, Lisa, Voss, Gerald, Altfeld, Marcus
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241906/
https://ncbi.nlm.nih.gov/pubmed/21963936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3182373b77
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