Cecal ligation and puncture followed by MRSA pneumonia increases mortality in mice and blunts production of local and systemic cytokines

Mortality in the ICU frequently results from the synergistic effect of two temporally-distinct infections. This study examined the pathophysiology of a new model of intraabdominal sepsis followed by methicillin-resistant Staphylococcus aureus (MRSA) pneumonia. Mice underwent cecal ligation and punct...

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Bibliographische Detailangaben
Hauptverfasser: Jung, Enjae, Perrone, Erin E., Liang, Zhe, Breed, Elise R., Dominguez, Jessica A., Clark, Andrew T., Fox, Amy C., Dunne, W. Michael, Burd, Eileen M., Farris, Alton B., Hotchkiss, Richard S., Coopersmith, Craig M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241900/
https://ncbi.nlm.nih.gov/pubmed/21937950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3182360faf
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