Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure

Many cells die during development, tissue homeostasis, and disease. Dysregulation of apoptosis leads to cranial neural tube closure (NTC) defects like exencephaly, although the mechanism is unclear. Observing cells undergoing apoptosis in a living context could help elucidate their origin, behavior,...

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Bibliographische Detailangaben
Hauptverfasser: Yamaguchi, Yoshifumi, Shinotsuka, Naomi, Nonomura, Keiko, Takemoto, Kiwamu, Kuida, Keisuke, Yosida, Hiroki, Miura, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2011
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241723/
https://ncbi.nlm.nih.gov/pubmed/22162136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104057
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