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Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure
Many cells die during development, tissue homeostasis, and disease. Dysregulation of apoptosis leads to cranial neural tube closure (NTC) defects like exencephaly, although the mechanism is unclear. Observing cells undergoing apoptosis in a living context could help elucidate their origin, behavior,...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241723/ https://ncbi.nlm.nih.gov/pubmed/22162136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104057 |
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