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Dual role of interleukin-17 in pannus growth and osteoclastogenesis in rheumatoid arthritis

INTRODUCTION: In a murine model, interleukin (IL)-17 plays a critical role in the pathogenesis of arthritis. There are controversies, however, regarding whether IL-17 is a proinflammatory mediator in rheumatoid arthritis (RA). We previously established an ex vivo cellular model using synovial tissue...

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Detalhes bibliográficos
Main Authors: Ito, Hiroshi, Yamada, Hidehiro, Shibata, Toshiko N, Mitomi, Hirofumi, Nomoto, So, Ozaki, Shoichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241358/
https://ncbi.nlm.nih.gov/pubmed/21294864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3238
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