The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration

INTRODUCTION: Recent evidence suggests that intervertebral disc (IVD) cells derived from degenerative tissue are unable to respond to physiologically relevant mechanical stimuli in the 'normal' anabolic manner, but instead respond by increasing matrix catabolism. Understanding the nature o...

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Dades bibliogràfiques
Autors principals: Gilbert, Hamish TJ, Hoyland, Judith A, Freemont, Anthony J, Millward-Sadler, Sarah J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241352/
https://ncbi.nlm.nih.gov/pubmed/21276216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3229
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