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Independent and Combined Effects of Exercise Training and Metformin on Insulin Sensitivity in Individuals With Prediabetes

OBJECTIVE: Physical activity or metformin enhances insulin sensitivity and opposes the progression from prediabetes to type 2 diabetes. The combination may be more effective because each treatment stimulates AMP-activated protein kinase activity in skeletal muscle. We evaluated the effects of exerci...

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Bibliographic Details
Main Authors: Malin, Steven K., Gerber, Robert, Chipkin, Stuart R., Braun, Barry
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241331/
https://ncbi.nlm.nih.gov/pubmed/22040838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-0925
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