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Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
Astrocytes, together with microglia and macrophages, participate in innate inflammatory responses in the CNS. While inflammatory mediators such as interferons generated by astrocytes may be critical in the defense of the CNS, sustained unopposed cytokine signaling could result in harmful consequence...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241213/ https://ncbi.nlm.nih.gov/pubmed/22170100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21233 |
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