Ceruloplasmin Deficiency Results in an Anxiety Phenotype Involving Deficits in Hippocampal Iron, Serotonin and BDNF

Ceruloplasmin (Cp) is a ferroxidase involved in iron metabolism by converting Fe(2+) to Fe(3+), and by regulating cellular iron efflux. In the ceruloplasmin knockout (CpKO) mouse, the deregulation of iron metabolism results in moderate liver and spleen hemosiderosis, but the impact of Cp deficiency...

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Detalhes bibliográficos
Main Authors: Texel, Sarah J., Camandola, Simonetta, Ladenheim, Bruce, Rothman, Sarah M., Mughal, Mohamed R., Unger, Erica L., Cadet, Jean Lud, Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240727/
https://ncbi.nlm.nih.gov/pubmed/22035068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07554.x
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