Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development

Alternative splicing amplifies the information content of the genome, creating multiple mRNA isoforms from single genes. The evolutionarily conserved splicing activator Tra2β (Sfrs10) is essential for mouse embryogenesis and implicated in spermatogenesis. Here we find that Tra2β is up-regulated as t...

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Detalhes bibliográficos
Main Authors: Grellscheid, Sushma, Dalgliesh, Caroline, Storbeck, Markus, Best, Andrew, Liu, Yilei, Jakubik, Miriam, Mende, Ylva, Ehrmann, Ingrid, Curk, Tomaz, Rossbach, Kristina, Bourgeois, Cyril F., Stévenin, James, Grellscheid, David, Jackson, Michael S., Wirth, Brunhilde, Elliott, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240583/
https://ncbi.nlm.nih.gov/pubmed/22194695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002390
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